Ryan Seacrest Is Replacing Pat Sajak as ‘Wheel of Fortune’ Host

Given how long Sajak and White have worked together, many viewers have wondered over the years whether or not the pair was ever romantically involved. It’s a question that White finally answered. Here’s a brief history of the hosts’ time on the show and their unique relationship.
Joining ‘Wheel of Fortune’
Pat Sajak joined Wheel of Fortune in December of 1981. A year later, Vanna White was also made part of the cast. She made it to the final round of casting over more than 200 other women who hoped to become the future letter flipper. Ultimately, White won out over Summer Bartholomew and Vicki McCarty, the other top choices for the role of hostess.

After testing each of the women on real episodes of the show, the producer decided that White was the one who activated the letters best of all the candidates. She quickly became very popular among viewers, particularly young adults. Many of her fans were interested in her dazzling show wardrobe. The phenomenon, known as “Vannamania,” swept through the United States, earning the new star numerous additional jobs outside of Wheel of Fortune.
Nearly 40 years together
For the next 40 years, White and Sajak would work intimately together as host and hostess of Wheel of Fortune. While they generally stuck to the same roles throughout this time, there were a few instances where they would swap, most notably in November 1996 when Sajak had laryngitis.

Despite their many years together, in 2020 Sajak admitted that he initially didn’t want White to be cast as the hostess. He said, “Not that she wasn’t lovely and wonderful and personable and all that. But she was the most nervous, by far, of any of them.”
White obviously proved him wrong and has done a wonderful job. It helped that the pair seems to have such incredible chemistry together. It’s this very chemistry which has caused many fans to question just what kind of relationship White and Sajak had outside of filming.
Friends or more?
It is well known that White and Sajak get along well – extremely well, in fact. According to White herself, they rarely disagree on anything except whether ketchup should be put on a hot dog. Yet despite their closeness, White has emphasized that they really are just best friends and there is nothing romantic going on between them. The closest the two have come to being involved was when they played a prank on their audience.

“Years and years ago, we did an April Fool’s joke,” White recalled. “I don’t know that we said we were married, but we said something about being together, and we received toasters…” Sajak added later that it took years for people to stop sending the “married couple” Crockpots.
So although the renowned Wheel of Fortune stars have been together, in a work sense, for longer than most couples, they are not, and have never been, in a romantic relationship.
Nearly 20 years without a raise?
Soon after Sajak announced his retirement, fans were stunned to learn that Vanna White has not gotten a pay raise in 18 years. This surprising revelation comes from Puck reporter Matthew Belloni, who says that White, 66, has hired an aggressive lawyer to negotiate a raise as her current deal concludes at the end of the 2023-24 season.

Puck’s report states that White currently earns $3 million annually, while Sajak earns five times more than that. While some argue that Sajak is the host while White is a co-host responsible only for revealing letters on the board, Puck asserts that White engages in significantly more publicity for the show than Sajak. Sony, the show’s production company, declined to comment on Puck’s findings.
Whoopi Goldberg from The View expressed interest in taking over Sajak’s role, and several other notable names, including Ryan Seacrest and Sajak’s daughter Maggie, were mentioned as potential candidates.
Seacrest was named the new host of ‘Wheel’
The New York Times and other media outlets reported on June 27 that Ryan Seacrest will take over as the host of Wheel of Fortune. The news comes just two weeks after Sajak’s announcement. Seacrest, 48, is a talk show veteran himself, having hosted and produced many other programs including American Idol and Live with Kelly and Ryan.

“I’m truly humbled to be stepping into the footsteps of the legendary Pat Sajak,” Seacrest said in a statement. “I can say, along with the rest of America, that it’s been a privilege and pure joy to watch Pat and Vanna on our television screens for an unprecedented 40 years, making us smile every night and feel right at home with them.”
Seacrest will also act as a consulting producer on the show.

We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth

The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.

A dental breakthrough

While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.

A bit of science

The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.

As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.

On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.

BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.

“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.

The first results

Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.

“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.

Fully regrown frontal teeth in ferrets

The next steps

Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontiaa genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.

Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.

“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”

So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.

Preview photo credit KyotoU_News / Twitter

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