It’s crucial now more than ever to keep an eye out for dogs left in hot automobiles because summer is still going strong and temperatures are rising to record levels in many places.
Dogs who are left in hot cars will not survive for long due to their severe susceptibility to heat stroke. Accidents can still occur even if you believe you have done all the necessary safety measures to avert catastrophe.
That was the unfortunate situation that occurred recently when a police department K9 was left in a hot car without air conditioning and without emergency procedures in place, leading to his death.
Vader, a 4-year-old K9 with the Arnold Police agency in Missouri, passed away on July 31 from heat exhaustion, according to a press release from the agency.
Vader was left in a running patrol car with the air conditioner running, according to the department, which referred to this as a “necessary and common practice” for K9s who are not actively participating in police operations.
Officers found that the air conditioning system had broken down when they got back inside the car.
The police added that although all of their K9 patrol cars have a failsafe mechanism that sounds the horn, pulls down the windows, warns the handler, and triggers the alarms and sirens if the vehicle reaches a particular temperature, this emergency backup “failed to activate.”
After being taken to the veterinary facility in a hurry, Vader appeared to be improving, but he eventually passed away.
The Arnold Police Department posted, “Unfortunately, we learned last night that there were no further treatments available for Vader and he succumbed to his injuries.”
“Investigating this tragedy to determine what went wrong,” the department wrote in a letter. They also requested that people remember Vader’s handler and his family in their prayers and expressed their sorrow over his passing.
Understandably, the public has been devastated by the news and has experienced strong emotions; many have wondered if more might have been done to avert this disaster.
On Facebook, someone said, “Take the dog with you, just like a child. Common practice needs to change.”
For that reason alone, another person remarked, “These dogs should never be left in a car for an extended period of time, running or not.” “I know it was an accident, but nobody else should have to go through this.”
Others recommended enhancing or testing the emergency heat alarm system of the cars more frequently because it did not sound.
Vader is sadly not the only police dog to pass away after being left in a hot car; sadly, this happens frequently due to either officer negligence or—in this case—a malfunctioning air conditioner and backup system.
Horus, a second Missouri police dog, also passed away after being left in a hot car overnight, a few days before Vader did.
It is terrible that police dogs could suffer and even perish from a hot car since they put their lives in danger for their communities. Although emergency warnings and air conditioning are features of patrol cars, it is obvious that these devices are not infallible.
We hope that Vader’s untimely passing and the deaths of all the other K9 victims will spur more measures to safeguard their lives. 
We’ve All Waited for It: Scientists Created a Drug That Can Help Regrow Lost Teeth
The tooth fairy is a welcome guest for any child who has lost a tooth. Not only will the fairy leave a small gift under the child’s pillow, but they be assured of a replacement tooth in a few months. Unfortunately, the scenario is quite different for adults grappling with a loss of teeth. Luckily, there may be some hope thanks to a new study performed by scientists at Kyoto University and the University of Fukui.
A dental breakthrough
While the typical adult mouth houses 32 teeth, approximately 1% of the population exhibits variations of them, either possessing more or fewer teeth due to congenital conditions. Researchers have delved into the genetic factors behind cases of excessive teeth, seeking valuable insights into the potential regeneration of teeth in adults. This study is the first to show that monoclonal antibodies can help regrow teeth. It suggests a new way to treat a dental problem that currently requires implants and other artificial solutions.
A bit of science
The research team disclosed that an antibody targeting a specific gene, known as uterine sensitization-associated gene-1 (USAG-1), can induce tooth development in mice affected by tooth agenesis, a congenital condition. The findings were published in the journal, Science Advances.
As per Katsu Takahashi, a senior lecturer at the Kyoto University Graduate School of Medicine and one of the principal contributors to the study, the essential molecules crucial for the development of teeth have already been pinpointed. “The morphogenesis of individual teeth depends on the interactions of several molecules including BMP, or bone morphogenetic protein, and Wnt signaling,” says Takahashi.
On April 13, 2021, the University of Kyoto posted its first pic of newly-grown teeth in mice.
BMP and Wnt are involved in more than just tooth development; they affect the growth of organs and tissues early in the body’s development. Because drugs affecting them directly might have broad side effects, scientists are cautious. To find a potentially safer method, researchers focused on the gene USAG-1, thinking that aiming at factors countering BMP and Wnt specifically in tooth development could be more precise.
“We knew that suppressing USAG-1 benefits tooth growth. What we did not know was whether it would be enough,” added Takahashi.
The first results
Scientists looked at how different monoclonal antibodies affect USAG-1. Monoclonal antibodies are often used to treat things like cancer and arthritis and for making vaccines. Tests with this antibody showed that BMP signaling is crucial for deciding the number of teeth in mice. Also, just one treatment was enough to grow a whole tooth. Further tests confirmed these positive results in ferrets too.
“Ferrets are diphyodont animals with similar dental patterns to humans. Our next plan is to test the antibodies on other animals, such as pigs and dogs,” explained Takahashi.
Fully regrown frontal teeth in ferrets
The next steps
Now, scientists are going to test the drug on healthy adults. If that goes well, the team plans to try it on kids aged 2 to 6 with a rare tooth problem called anodontia, a genetic disorder defined as the absence of all teeth. These kids will get one shot of the drug to see if it makes their teeth grow. If everything works out, the medicine might be approved by 2030.
Takahashi sees the new medicine as an additional choice for individuals who are missing some or all of their teeth.
“The idea of growing new teeth is every dentist’s dream,” Takahashi told the Japanese newspaper, The Mainichi in June this year. “I’ve been working on this since I was a graduate student. I was confident I’d be able to make it happen.”
So hopefully, by the year 2030, humans will get a chance to have their third generation of teeth grown and say goodbye to implants. Until then, make sure to keep your teeth strong and healthy — this article will help you with that.
Preview photo credit KyotoU_News / Twitter
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